Kidney Failure

Prof. Dr. Abdulmuttalip Şimşek

Kidney Failure

Kidney failure is a serious health problem that arises when the kidneys cannot adequately filter waste substances from the blood and cannot remove these substances from the body. The disease can occur in an acute (sudden onset) or chronic (slowly progressing) form. Chronic kidney failure in particular can progress without symptoms for a long time, and for this reason most patients are diagnosed at an advanced stage.

Among the main functions of the kidneys are filtering waste substances such as urea and creatinine, maintaining the body’s water and electrolyte balance, and contributing to the regulation of blood pressure. When these functions are impaired, toxic substances accumulate in the body and serious clinical conditions affecting many systems develop.

Early and Advanced Stage Symptoms

Signs that can be seen in the early stage:

  • Fatigue and tiring quickly
  • Decreased appetite
  • Mild edema (especially in the feet)
  • Frequent urination or getting up to urinate at night

In the more advanced stages:

  • Marked tiredness and weakness
  • Nausea and vomiting
  • Swelling in the legs and around the eyes
  • Shortness of breath
  • High blood pressure
  • Difficulty concentrating and a deterioration in general condition

The Most Common Causes of Kidney Failure

  • Diabetes
  • Hypertension
  • Recurrent kidney infections
  • Advanced kidney stone disease
  • Genetic kidney diseases
  • Long-term use of certain medications

Treatment Approach

Treatment is planned according to the stage of the disease:

Early stage:

  • Blood sugar and blood pressure control
  • A kidney-friendly diet (protein and salt control)
  • Medication treatment
  • Regular follow-up and laboratory checks

Advanced stage:

  • Dialysis treatment
  • Kidney transplant

In chronic kidney failure, the main aim is to slow the progression of the loss of kidney function and to preserve the patient’s quality of life.

Frequently Asked Questions

Acute kidney failure can recover completely if treated early. However, in chronic kidney failure the damage is usually permanent, and progression is slowed with treatment.

Because the kidneys can work at high capacity for a long time. For this reason, even if function decreases, it may not cause symptoms in the early stage.

Dialysis becomes necessary when kidney functions drop to a critical level and the accumulation of toxins in the body cannot be controlled.

Unless a kidney transplant is performed, it can continue long-term or for a lifetime in most patients.

Adequate water consumption is important for kidney health, but it is not protective on its own. Diabetes and blood pressure control play a more critical role.

Salt and protein intake, fluid balance, medication use and regular doctor check-ups are of great importance.

When untreated, it can lead to serious consequences. However, thanks to early diagnosis, dialysis and transplant options, life expectancy and quality of life can be significantly increased.

Clinical Importance

When kidney failure is caught in the early stage, its progression can be slowed. For this reason, it is vital, especially for diabetes and hypertension patients, to have regular kidney function tests.

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